Can not open open multiple browsers if I use -no-remote -profile

[waifile]

I use this profile in shortcut:
C:\Program Files\Mozilla\Palemoon.exe -no-remote -profile "D:\Mozilla-Default-User-1"

After I opened one browser, I click the icon again it will popup show "Pale Moon is already running, but is not responding. The old pale Moon process must be closed to open a new window".

How would I be able to open multiple browsers?

Thank you.

[Moonchild]

You can't share a profile between concurrently running copies of the browser (for obvious reasons of write conflict).
Each independent browser will have to have its own distinct profile.

[waifile]

shortcut: C:\Program Files\Mozilla\Palemoon.exe can open multiple browsers from D:\Mozilla-Default-User
Is there any way open multiple browsers from D:\Mozilla-Default-User-1?
Thank you for your reply.

[Moonchild]

If you don't include "no-remote" then you aren't actually opening a separate browser instance, merely a second window in the same browser instance.
So no, you can't actually open multiple instances of the same browser on the same profile.

I'm not sure what kind of workflow you are looking at using but if you need multiple separate instances of the browser, you need multiple profiles for it (one for each).
If you don't actually need pure separation you can just open multiple windows from within the browser itself (with Ctrl+N).
If you DO, e.g. for multiple separate account environments, may I suggest you use multiple copies of the portable browser instead, that keep their profile "with them"?

[waifile]

I will try the portable browser. thank you.