Get past: Error: Access was denied while trying to open files in your profile directory.

[dakra]

This is an old problem, but the suggestions in https://forum.palemoon.org/viewtopic.php?f=37&t=3782&p=22231&hilit=Access+denied+profile+directory.#p22231 did not work for me.

What did the trick were:

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sudo chown -R "$USER:$USER" "$HOME"

as suggested in https://forum.palemoon.org/viewtopic.php?f=37&t=10534&p=73565&hilit=chown#p73565
and

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palemoon -no-remote -ProfileManager

as suggested in https://forum.palemoon.org/viewtopic.php?f=3&t=11612&p=81842&hilit=profile#p81842

[ipsirc]

Which filesystem do you use for profile? I experienced the same access denied on overlayfs.